Sune Karl Bergström (January 10, 1916 in Stockholm, Sweden – August 15, 2004) was a Swedish biochemist.

In 1975, he was appointed to the Nobel Foundation Board of Directors in Sweden.

In 1975, he was awarded the Louisa Gross Horwitz Prize from Columbia University together with Bengt I. Samuelsson. He shared the Nobel Prize in Physiology or Medicine with Bengt I. Samuelsson and John R. Vane in 1982, for discoveries concerning prostaglandins and related substances.

He was elected a member of the Royal Swedish Academy of Sciences in 1965, and its President in 1983. In 1965, he was also elected a member of the Royal Swedish Academy of Engineering Sciences.

Sune Bergström was the father of the evolutionary geneticist Svante Pääbo and of the businessman Rurik Bergström. He was an honorary member of the International Academy of Science.