Sultan Hussein Kamel (Arabic: السلطان حسين كامل‎; 21 November 1853 – 9 October 1917) was the Sultan of Egypt from 19 December 1914 to 9 October 1917, during the British protectorate over Egypt.

Hussein Kamel was the son of Khedive Isma'il Pasha, who ruled Egypt from 1863 to 1879. Hussein Kamel was granted the title of Sultan of Egypt by the British in 1914, after they had deposed his nephew, Khedive Abbas Hilmi II. The newly created Sultanate of Egypt was declared a British protectorate. This brought to an end the legal fiction of Ottoman sovereignty over Egypt, which had been largely nominal since Muhammad Ali's seizure of power in 1805.

Upon Hussein Kamel's death, his only son, Prince Kamal al-Din Husayn, declined the succession, and Hussein Kamel's brother Ahmed Fuad ascended the throne as Fuad I. At the beginning of Naguib Mahfouz's novel Palace Walk, Ahmad Abd al-Jawwad says "What a fine man Prince Kamal al-Din Husayn is! Do you know what he did? He refused to ascend the throne of his late father so long as the British are in charge."