Born in Paris, Collot left his home in the rue St. Jacques in his teens to join the travelling theatres of provincial France. His moderately successful career as an actor, supplemented by a vigorous outpouring of works for the stage, took him from Bordeaux in the south of France to Nantes in the west and Lille in the north and even into the Dutch Republic, where he met his wife.

In 1784 he became director of the theatre in Geneva, Switzerland, and then at the prestigious playhouse at Lyon in 1787. At the outbreak of the Revolution in 1789 he dropped everything and returned to Paris, where his lead actor's voice, his writing skills, and his ability to organise and direct large scale fêtes (civic feasts) were to make him famous.

He contributed to revolutionary agitation from the very beginning; but it was not until 1791 that he became a figure of importance. With the publication of L'Almanach du Père Gérard, a book advocating a constitutional monarchy in popular terms, he suddenly acquired great popularity.

His fame was soon increased by his involvement on behalf of the Swiss of the Château - Vieux Regiment, condemned to the galleys for mutiny at Nancy. Collot d'Herbois' efforts resulted in their freedom; he went to Brest in search of them; and a civic feast was held on his behalf and theirs, which occasioned for a poem by André de Chénier.

His opinions became more and more radical. Collot d'Herbois was a member of the Paris Commune during the insurrection of 10 August 1792, and was elected deputy for Paris to the National Convention. On the first day of the Convention (21 September 1792) he was the first to demand the abolition of the French monarchy. Collot d'Herbois later voted for the death of Louis XVI "sans sursis" ("without delay").

He was engaged in the struggle between the Mountain and the Girondists. After François Hanriot's coup d'état of 31 May 1793, he was conspicuous in his attack on the defeated Girondist party. Along with his close friend Billaud - Varenne, he sat at the extreme left of the Convention, attacking speculators, and proposing egalitarian programmes. In June, he was made president of the Convention; and in September he joined the Committee of Public Safety, where he was active as a sort of general secretary.

After having entrusted him with several missions to Nice, Nevers, and Compiègne, the Convention sent him along with Joseph Fouché, on 30 October 1793, to punish the revolt of Lyon. There, he introduced the Reign of Terror in its most violent form, with mass executions, including more than a hundred priests and nuns, and beginning the dismantling of the city itself. His excessive behavior led the Committee of Public Safety to have Collot return to Paris as a suspect.

In May 1794, assassination attempts on Collot and Maximilien Robespierre only increased his popularity. As Collot was accused of excessive slaughter and destruction and he suspected that he might soon be arrested and executed, he opposed Robespierre during the Thermidorian Reaction, when he presided over the Convention during the initial session. Ironically considering this change of heart (previously the two had been colleagues on the Committee of Public Safety), Collot d'Herbois was accused of complicity with the fallen leader, but was acquitted. Denounced a second time, he defended himself by pleading that he had acted for the Revolution, but in March 1795 he was condemned with Bertrand Barère de Vieuzac and Billaud - Varenne to transportation to Cayenne, French Guiana, where he exerted a brief revolutionary influence before dying of yellow fever in 1796.

Beginning his literary career in 1772 with the critically acclaimed Lucie, ou les Parents imprudents and finishing in 1792 with L'Aîné et le cadet, Collot was an accomplished, if minor, dramatist in a turbulent period of the French stage.

Before the Revolution he wrote at least fifteen plays, of which ten survive, including Lucie, an adaptation of William Shakespeare's The Merry Wives of Windsor (as M. Rodomont, ou l'Amant loup - garou), and an adaptation of Pedro Calderón de la Barca's El Alcalde de Zalamea (Il y a bonne justice, ou le Paysan magistrat), all three of which kept the stage throughout France for over a decade. During the first three years of the Revolution he wrote at least seven more plays, of which six survive, juggling the tearful love themes of le drame bourgeois with political themes and messages in such plays as L'Inconnu, ou le Préjugé vaincu and Socrate (on Socrates).

In 1791 he wrote the prize winning L'Almanach de père Gérard, a fictional account of revolutionary morality which went on to become the best seller of the period, establishing his political credentials in the process.

He was also one of the authors of the first French republican Constitution, which was written in 1793 but never applied.