In 1909, Kwame Nkrumah was born to Madam Nyaniba in Nkroful, Gold Coast. Nkrumah graduated from the Achimota School in Accra in 1930, studied at a Roman Catholic seminary, and taught at a Catholic school in Axim. In 1935 he left Ghana for the United States, receiving a BA from Lincoln University, Pennsylvania, in 1939, where he pledged the Mu Chapter of Phi Beta Sigma fraternity, and received a Bachelor of Sacred Theology in 1942. Nkrumah earned a Master of Science in education from the University of Pennsylvania in 1942, and a Master of Arts in philosophy the following year. While lecturing in political science at Lincoln he was elected president of the African Students Organization of America and Canada. As an undergraduate at Lincoln he participated in at least one student theater production and published an essay on European government in Africa in the student newspaper, The Lincolnian.

During his time in the United States, Nkrumah preached at black Presbyterian Churches in Philadelphia and New York City. He read books about politics and divinity, and tutored students in philosophy. Nkrumah encountered the ideas of Marcus Garvey and in 1943 met and began a lengthy correspondence with Trinidadian Marxist C.L.R. James, Russian expatriate Raya Dunayevskaya, and Chinese - American Grace Lee Boggs, all of whom were members of a US based Trotskyist intellectual cohort. Nkrumah later credited James with teaching him 'how an underground movement worked'.

He arrived in London in May 1945 intending to study at the LSE. After meeting with George Padmore, he helped organize the Fifth Pan - African Congress in Manchester, England. Then he founded the West African National Secretariat to work for the decolonization of Africa. Nkrumah served as Vice - President of the West African Students' Union (WASU).

In the autumn of 1947, Nkrumah was invited to serve as the General Secretary to the United Gold Coast Convention (UGCC) under Joseph B. Danquah. This political convention was exploring paths to independence. Nkrumah accepted the position and sailed for the Gold Coast. After brief stops in Sierra Leone, Liberia, and the Ivory Coast, he arrived in the Gold Coast in December 1947.

In February 1948, police fired on African ex - servicemen protesting the rising cost of living. The shooting spurred riots in Accra, Kumasi, and elsewhere. The government suspected the UGCC was behind the protests and arrested Nkrumah and other party leaders. Realizing their error, the British soon released the convention leaders. After his imprisonment by the colonial government, Nkrumah emerged as the leader of the youth movement in 1948.

After his release, Nkrumah hitchhiked around the country. He proclaimed that the Gold Coast needed "self - government now", and built a large power base. Cocoa farmers rallied to his cause because they disagreed with British policy to contain swollen shoot disease. He invited women to participate in the political process at a time when women's suffrage was new to Africa. The trade unions also allied with his movement. By 1949, he organized these groups into a new political party: The Convention People's Party.

The British convened a selected commission of middle class Africans to draft a new constitution that would give Ghana more self - government. Under the new constitution, only those with sufficient wage and property would be allowed to vote. Nkrumah organized a "People's Assembly" with CPP party members, youth, trade unionists, farmers, and veterans. They called for universal franchise without property qualifications, a separate house of chiefs, and self - governing status under the Statute of Westminster 1931. These amendments, known as the Constitutional Proposals of October 1949, were rejected by the colonial administration.

When the colonial administration rejected the People's Assembly's recommendations, Nkrumah organized a "Positive Action" campaign in January 1950, including civil disobedience, non - cooperation, boycotts, and strikes. The colonial administration arrested Nkrumah and many CPP supporters, and he was sentenced to three years in prison.

Facing international protests and internal resistance, the British decided to leave the Gold Coast. Britain organized the first general election to be held under universal franchise on 5 – 10 February 1951. Though in jail, Nkrumah's CPP was elected by a landslide taking 34 out of 38 elected seats in the Legislative Assembly. Komla Agbeli Gbedemah is credited with organizing Nkrumah's entire campaign while he (Nkrumah) was still in prison at Fort James. Nkrumah was released from prison on 12 February, and summoned by the British Governor Charles Arden - Clarke, and asked to form a government on the 13th. The new Legislative Assembly met on 20 February, with Nkrumah as Leader of Government Business, and E.C. Quist as President of the Assembly. A year later, the constitution was amended to provide for a Prime Minister on 10 March 1952, and Nkrumah was elected to that post by a secret ballot in the Assembly, 45 to 31, with eight abstentions on 21 March. He presented his "Motion of Destiny" to the Assembly, requesting independence within the British Commonwealth "as soon as the necessary constitutional arrangements are made" on 10 July 1953, and that body approved it.

As a leader of this government, Nkrumah faced many challenges: first, to learn to govern; second, to unify the four territories of the Gold Coast; third, to win his nation’s complete independence from the United Kingdom. Nkrumah was successful at all three goals. Within six years of his release from prison, he was the leader of an independent nation.

At 12 a.m. on 6 March 1957, Nkrumah declared Ghana independent. He was hailed as the Osagyefo - which means "redeemer" in the Twi language.

On 6 March 1960, Nkrumah announced plans for a new constitution which would make Ghana a republic. The draft included a provision to surrender Ghanaian sovereignty to a Union of African States. On 19, 23, and 27 April 1960 a presidential election and plebiscite on the constitution were held. The constitution was ratified and Nkrumah was elected president over J.B. Danquah, the UP candidate, 1,016,076 to 124,623.

In 1961, Nkrumah laid the first stones in the foundation of the Kwame Nkrumah Ideological Institute created to train Ghanaian civil servants as well as promote Pan - Africanism. In 1964, all students entering college in Ghana were required to attend a two week "ideological orientation" at the Institute. Nkrumah remarked that "trainees should be made to realize the party's ideology is religion, and should be practiced faithfully and fervently."

In 1963, Nkrumah was awarded the Lenin Peace Prize by the Soviet Union. Ghana became a charter member of the Organization of African Unity in 1963.

The Gold Coast had been among the wealthiest and most socially advanced areas in Africa, with schools, railways, hospitals, social security and an advanced economy. Under Nkrumah’s leadership, Ghana adopted some socialist policies and practices. Nkrumah created a welfare system, started various community programs, and established schools.

He generally took a non-aligned Marxist perspective on economics, and believed capitalism had malignant effects that were going to stay with Africa for a long time. Although he was clear on distancing himself from the African socialism of many of his contemporaries, Nkrumah argued that socialism was the system that would best accommodate the changes that capitalism had brought, while still respecting African values. He specifically addresses these issues and his politics in a 1967 essay entitled "African Socialism Revisited":

"We know that the traditional African society was founded on principles of egalitarianism. In its actual workings, however, it had various shortcomings. Its humanist impulse, nevertheless, is something that continues to urge us towards our all - African socialist reconstruction. We postulate each man to be an end in himself, not merely a means; and we accept the necessity of guaranteeing each man equal opportunities for his development. The implications of this for socio - political practice have to be worked out scientifically, and the necessary social and economic policies pursued with resolution. Any meaningful humanism must begin from egalitarianism and must lead to objectively chosen policies for safeguarding and sustaining egalitarianism. Hence, socialism. Hence, also, scientific socialism."

Nkrumah was also perhaps best known politically for his strong commitment to and promotion of Pan - Africanism. He was inspired by the writings of black intellectuals like Marcus Garvey, W.E.B. Du Bois, and George Padmore, and his relationships with them. Nkrumah's biggest success in this area was perhaps his significant influence in the founding of the Organization of African Unity.

Nkrumah attempted to rapidly industrialize Ghana's economy. He reasoned that if Ghana escaped the colonial trade system by reducing dependence on foreign capital, technology, and material goods, it could become truly independent. However, overspending on capital projects caused the country to be driven deeply into debt — estimated as much as $1 billion USD by the time he was ousted in 1966.

The year 1954 was a pivotal year during the Nkrumah era. In that year's independence elections, he tallied some of the independence election vote. However, that same year saw the world price of cocoa rise from £150 to £450 per ton. Rather than allowing cocoa farmers to maintain the windfall, Nkrumah appropriated the increased revenue via federal levies, then invested the capital into various national development projects. This policy alienated one of the major constituencies that helped him come to power.

In 1958 Nkrumah introduced legislation to restrict various freedoms in Ghana. After the Gold Miners' Strike of 1955, Nkrumah introduced the Trade Union Act, which made strikes illegal. When he suspected opponents in parliament of plotting against him, he wrote the Preventive Detention Act that made it possible for his administration to arrest and detain anyone charged with treason without due process of law in the judicial system. Prisoners were often held without trial, and their only legal method of recourse was personal appeal to Nkrumah himself.

When the railway workers went on strike in 1961, Nkrumah ordered strike leaders and opposition politicians arrested under the Trade Union Act of 1958. While Nkrumah had organized strikes just a few years before, he now opposed industrial democracy because it conflicted with rapid industrial development. He told the unions that their days as advocates for the safety and just compensation of miners were over, and that their new job was to work with management to mobilize human resources. Wages must give way to patriotic duty because the good of the nation superseded the good of individual workers, Nkrumah's administration contended.

The Detention Act led to widespread disaffection with Nkrumah’s administration. Some of his associates used the law to arrest innocent people to acquire their political offices and business assets. Advisers close to Nkrumah became reluctant to question policies for fear that they might be seen as opponents. When the clinics ran out of pharmaceuticals, no one notified him. Some people believed that he no longer cared. Police came to resent their role in society, particularly after Nkrumah superseded most of their duties and responsibilities with his personal guard - the National Security Service and presidential Guard regiments. Nkrumah disappeared from public view out of a justifiable fear of assassination following multiple attempts on his life. In 1964, he proposed a constitutional amendment making the CPP the only legal party and himself president for life of both nation and party. The amendment passed with 99.91 percent of the vote, an implausibly high total that could have only been obtained through fraud. Indeed, observers condemned the vote as "obviously rigged." In any event, Ghana had effectively been a one - party state since independence. The amendment transformed Nkrumah's presidency into a de facto legal dictatorship.

Nkrumah's advocacy of industrial development at any cost, with help of longtime friend and Minister of Finance, Komla Agbeli Gbedema, led to the construction of a hydroelectric power plant, the Akosombo Dam on the Volta River in eastern Ghana. Kaiser Aluminum agreed to build the dam for Nkrumah, but restricted what could be produced using the power generated. Nkrumah borrowed money to build the dam, and placed Ghana in debt. To finance the debt, he raised taxes on the cocoa farmers in the south. This accentuated regional differences and jealousy. The dam was completed and opened by Nkrumah amidst world publicity on 22 January 1966. Nkrumah appeared to be at the zenith of his power, but the end of his regime was only days away.

Nkrumah wanted Ghana to have modern armed forces, so he acquired aircraft and ships, and introduced conscription. He also gave military support to those fighting the Smith administration in Zimbabwe, then called Rhodesia. In February 1966, while Nkrumah was on a state visit to North Vietnam and China, his government was overthrown in a military coup led by Emmanuel Kwasi Kotoka and the National Liberation Council. Several commentators, such as John Stockwell, have claimed the coup received support from the CIA.

Nkrumah never returned to Ghana, but he continued to push for his vision of African unity. He lived in exile in Conakry, Guinea, as the guest of President Ahmed Sékou Touré, who made him honorary co-president of the country. He read, wrote, corresponded, gardened, and entertained guests. Despite retirement from public office, he was still frightened of western intelligence agencies. When his cook died, he feared that someone would poison him, and began hoarding food in his room. He suspected that foreign agents were going through his mail, and lived in constant fear of abduction and assassination. In failing health, he flew to Bucharest, Romania, for medical treatment in August 1971. He died of skin cancer in April 1972 at the age of 62.

Nkrumah was buried in a tomb in the village of his birth, Nkroful, Ghana. While the tomb remains in Nkroful, his remains were transferred to a large national memorial tomb and park in Accra.

Over his lifetime, Nkrumah was awarded honorary doctorates by Lincoln University, Moscow State University; Cairo University in Cairo, Egypt; Jagiellonian University in Kraków, Poland; Humboldt University in the former East Berlin; and many other universities.

In 2000, he was voted Africa's man of the millennium by listeners to the BBC World Service.